Prior Exposure to Aged and Diluted Sidestream Cigarette Smoke Impairs Bronchiolar Injury and Repair

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Prior exposure to aged and diluted sidestream cigarette smoke impairs bronchiolar injury and repair.

The bronchiolar injury/repair response to naphthalene (NA) in mice includes acute distal airway epithelial injury that is followed by epithelial proliferation and redifferentiation, which result in repair of the epithelium within 14 days. To test whether prior exposure to aged and diluted sidestream cigarette smoke (TS) would alter the injury/repair response of the airway epithelium, adult mice...

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Short-term exposure to aged and diluted sidestream cigarette smoke enhances ozone-induced lung injury in B6C3F1 mice.

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Sidestream cigarette smoke toxicity increases with aging and exposure duration.

OBJECTIVES To determine the effects of aging on the toxicity of sidestream tobacco smoke, the complex chemical mixture that enters the air from the lit end of burning cigarettes and constitutes the vast bulk of secondhand smoke. DESIGN Statistical analysis of data from controlled experimental exposures of Sprague Dawley rats to fresh and aged (for more than 30 minutes) sidestream smoke for up...

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Sidestream cigarette smoke and cardiac autonomic regulation

BACKGROUND The literature has already demonstrated that cigarette influences the cardiovascular system. In this study, we performed a literature review in order to investigate the relationship between sidestream cigarette smoke (SSCS) and cardiac autonomic regulation. METHODS Searches were performed on Medline, SciELO, Lilacs and Cochrane databases using the crossing between the key-words: "c...

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Sidestream cigarette smoke exposure effects on baroreflex in adult rats.

BACKGROUND It has been evidenced in the literature that exposure to cigarette smoke causes hypertension in rats; however, it has not been demonstrated if the baroreflex function is impaired before the animal becomes hypertensive. OBJECTIVE We evaluated short-term effects of sidestream cigarette smoke (SSCS) exposure on baroreflex function in Wistar normotensive rats. METHODS Rats were expos...

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ژورنال

عنوان ژورنال: Toxicological Sciences

سال: 2001

ISSN: 1096-6080,1096-0929

DOI: 10.1093/toxsci/60.1.152